2024 Fachinfo ganciclovir

Fachinfo ganciclovir

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WebGanciclovir, a nucleoside analog, can be enzymatically phosphorylated to an active triphosphate analog by herpes simplex virus thymidine kinase (HSV-TK). The … WebAug 31, 2024 · Ganciclovir ist ein Virostatikum aus der Klasse der Nukleosidanaloga, das zur Behandlung von Herpesviren verabreicht wird. Chemie Ganciclovir hat die …

ANHANG III ZUSAMMENFASSUNG DER MERKMALE …

WebMar 6, 2024 · Ganciclovir (gan sye' kloe vir) is an acyclic guanosine nucleoside analogue structurally related to acyclovir which has antiviral activity against many herpes viruses, including herpes … WebJede Durchstechflasche enthält 500 mg Ganciclovir (als Ganciclovir-Natrium). Nach Rekonstitution mit 10 ml Wasser für Injektionszwecke enthält jeder ml 50 mg … shipshewana indiana campgrounds

Valganciclovir: MedlinePlus Drug Information

WebGanciclovir is a synthetic analogue of 2′-deoxy-guanosine. It is first phosphorylated to ganciclovir monophosphate by a viral kinase encoded by the cytomegalovirus (CMV) … WebValganciclovir is also used to prevent cytomegalovirus (CMV) disease in people who have received a heart, kidney, or kidney-pancreas transplant and who have a chance of getting CMV disease. Valganciclovir is in a class of medications called antivirals. It works by preventing the spread of CMV disease or slowing the growth of CMV. WebGanciclovir is a DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye. Brand Names Cytovene, Zirgan Generic Name Ganciclovir DrugBank Accession Number DB01004 Background An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. quick access network drive

Reference ID: 4057706 - Food and Drug Administration

Ganciclovir. An update of its therapeutic use in cytomegalovirus ...

WebGanciclovir (9-[(1,3-dihydroxy-2-propoxy)methyl]guanine) is a potent inhibitor of viruses of the herpes family, including cytomegalovirus (CMV), that are pathogenic for humans and animals. The primary mechanism of ganciclovir action against CMV is inhibition of the replication of viral DNA by ganciclovir-5'-triphosphate (ganciclovir-TP). This inhi- WebValganciclovir, sold under the brand name Valcyte among others, is an antiviral medication used to treat cytomegalovirus (CMV) infection in those with HIV/AIDS or following organ transplant. It is often used long term as it only suppresses rather than cures the infection. Valganciclovir is taken by mouth. Common side effects include abdominal pain, … quick access network security key shipshewana indiana christmas parade

"WebWirkstoff: Ganciclovir 2. ZUSAMMENSETZUNG (ARZNEILICH WIRKSAMER BESTAND-TEIL NACH ART UND MENGE) 1 Injektionsflasche enthält 543mg Ganciclo-vir-Natrium … " - Fachinfo ganciclovir

Fachinfo ganciclovir

Valganciclovir Side Effects: Common, Severe, Long Term - Drugs.com

Websich Ganciclovir als mutagen, teratogen, aspermatogen, karzinogen und beein-trächtigte die Fertilität. Es gilt als wahr-scheinlich, dass Ganciclovir zu einer vor-übergehenden oder dauerhaften Hem-mung der Spermatogenese führt (siehe Abschnitte 4.6, 4.8 und 5.3). Ganciclovir sollte daher beim Menschen als potenziell WebJul 7, 2024 · Ganciclovir adalah obat antivirus yang digunakan dalam terapi infeksi sitomegalovirus ( cytomegalovirus / CMV). [1,2] Ganciclovir merupakan analog guanosin asiklik, yang memiliki struktur mirip dengan acyclovir. Ganciclovir perlu diaktivasi oleh trifosforilasi sebelum dapat menghambat polimerase DNA virus sehingga dapat …

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Webganciclovir levels at 30 min, 90 min, 6 h, and 11 h after ganciclovir infusion were 5.3 mg/L, 6.0 mg/L, 4.0 mg/L, and 3.5 mg/L, respectively; the estimated AUC 0–12 was 53.9 mg·h/L. The CMV load decreased from 5.0×106 to 5.3×104 copies/mL in parallel with the increase of platelet counts. The ganciclovir trough level and the estimated AUC WebThe use of ganciclovir warrants extreme caution, especially in the paediatric population due to the potential for long -term carcinogenicity and reproductive toxicity. The benefits of treatment should be carefully considered in each case and should clearly outweigh the risks (see section 4.2). Refer to

WebGanciclovir is a potential teratogen and carcinogen. Manufacturer advises avoid inhalation of the powder or direct contact of the powder or reconstituted solution with the … WebGanciclovir is an antiviral used in the treatment of severe viral infections, including cytomegalovirus (CMV). It is considered a potential teratogen and carcinogen in humans, …

Web011761-3641 Oktober 2013 Fachinformation Aciclovir-ratiopharm® 200 mg/400 mg/800 mg Tabletten 1 1. BEZEICHNUNG DER ARZNEIMITTEL Aciclovir-ratiopharm® 200 mg … Web819 rows · Ganciclovir is a DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye. Brand Names Cytovene, Zirgan Generic Name Ganciclovir …

WebValganciclovir wird nach oraler Anwendung rasch und umfassend zu Ganciclovir metabolisiert. Oral angewendetes Valganciclovir 900 mg zweimal täglich entspricht …

WebGANCICLOVIR INJECTION is indicated for the prevention of CMV disease in adult transplant recipients at risk for CMV disease [see Clinical Studies (14)]. 2 DOSAGE AND … quick access new employee orientationWebLa presentación de la inyección de ganciclovir es en polvo que se mezcla con líquido y se inyecta por vía intravenosa (en la vena). Generalmente se administra cada 12 horas. La duración del tratamiento depende de su salud en general, el tipo de infección que tenga y qué tan bien responde su cuerpo al medicamento. quick access new accountWebDec 17, 2024 · seeing floating spots before the eyes. shakiness in the legs, arms, hands, or feet. shortness of breath. slow or fast heartbeat. sore throat. trembling or shaking of the hands or feet. troubled breathing. troubled breathing with exertion. ulcers, sores, or white spots in the mouth. quick accessnews in anandabagar in banglaWebJan 23, 2024 · Ganciclovir is a polar hydrophilic compound with a solubility of 2.6 mg/mL in water at 25°C and an n-octanol/water partition coefficient of 0.022. The pKas for Ganciclovir are 2.2 and 9.4. … shipshewana indiana events 2022WebMay 9, 2024 · Congenital cytomegalovirus (cCMV) is one of the most common congenital infections and the leading cause of nongenetic childhood sensorineural hearing loss (SNHL) in the United States [].Antiviral treatment (ie, intravenous [IV] ganciclovir, oral valganciclovir) in infants with symptomatic cCMV disease has been shown to have … shipshewana indiana christmas lightsWebGanciclovir HEXAL® 500mg verschreibungspflichtig Fachinformation Gebrauchsinformation Weiter geht's nach Ihrer Anmeldung Um weitere Informationen … quick access new hiresWebGanciclovir. An update of its therapeutic use in cytomegalovirus infection. The antiviral nucleoside analogue ganciclovir has demonstrated in vitro activity against human … quick access new hire packet