Phospho irf3
WebApr 23, 2024 · We focused on the phosphorylation of IRF3, which is a downstream factor of the cGAS pathway . As shown in Figure 2A, the expression of phosphorylated-IRF3 (p-IRF3) was increased in HNSCC cells after X-ray irradiation, and cGAS knockdown suppressed the radiation-increased p-IRF3. These results suggest that ionizing radiation activates IRF3 ... WebPhospho-IRF-3 (Ser396) Antibody detects endogenous levels of IRF-3 only when phosphorylated at Ser396. This antibody does not cross-react with other family members … Monoclonal Antibody for studying IRF-3 (Ser396) phosphate. Cited in 635 …
Phospho irf3
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WebMar 30, 2024 · Similarly, the IRF7, IRF1, and phospho-IRF3 levels hiked after two days of SARS-CoV-2 infection. These findings suggested that IRF7, IRF1, and IRF3 were stimulated following HCoV infections. WebIRF-3 is a member of the interferon regulatory transcription factor (IRF) family. It mediates interferon-stimulated response element (ISRE) promoter activation and functions as a molecular switch for antiviral activity. DsRNA generated during the course of a viral infection leads to IRF-3 phosphorylation on the C-terminal serine/threonine cluster.
WebNational Center for Biotechnology Information WebJun 1, 2024 · IRF-3 Antibody (SL-12) is a mouse monoclonal IgG 1 κ IRF-3 antibody, cited in 73 publications, provided at 200 µg/ml raised against recombinant IRF-3 fusion protein corresponding to human IRF-3 (amino acids 56-427) IRF-3 Antibody (SL-12) is recommended for detection of IRF-3 of mouse, rat and human origin by WB, IP, IF and IHC …
Web"Phospho-IRF3 (Ser396) antibodies" comparison At Proteintech, we pride ourselves on our antibody quality, customer service and transparency. As such, we are comparing our antibodies with other vendors, enabling easy identification and comparisons of key data to help you choose the suitable antibody for your needs. WebJul 7, 2024 · Phospho-S365 acts as a docking site for IRF3, a transcription factor that is phosphorylated and activated by TBK1, leading to transcriptional induction of type I interferons (IFNs).
WebDetect and quantitate cellular phospho-IRF3 (Ser386) using a homogeneous AlphaLISA® SureFire® Ultra™ assay. We are now two standalone organizations Life Sciences & …
WebInvitrogen Anti-Phospho-IRF3 (Ser385) Polyclonal, Catalog # PA5-36775. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC … target candyIRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory phosphorylation sites. IRF3 is found … target candy filled easter eggsWebIntracellular Delivery of Lipopolysaccharide Induces Effective Th1-Immune Responses Independent of IL-12 Sachiko Watanabe1., Joe Inoue1,2*. 1Department of Biosciences, School of Science and Graduate School of Science, Kitasato University, Japan, 2Department of Immunology and Cell Biology, Graduate target candy hearts jarWebAll lanes : Anti-IRF3 (phospho S386) antibody [EPR2346] (ab76493) at 0.2 µg/ml (purified) Lane 1 : MCF7 (Human breast adenocarcinoma epithelial cell) whole cell lysates Lane 2 : … target cane chargerWebPhospho-IRF3 (Ser396) Antibody (BS-3195R) in WB Mouse liver lysates probed with Anti-IRF3 (Ser396) Polyclonal Antibody, Unconjugated (bs-3195R) at 1:300 overnight at 4°C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:5000 for 90 min at 37°C. Product Details Target Information target candlestick lampWeb环保商城会员企业上海邦景实业有限公司提供杂交瘤细胞;tbcd6规格, 细胞名称 杂交瘤细胞;tbcd6规格形态特性 淋巴母细胞样生长特性 半贴壁生长 特征特性 该细胞属保藏,其特征特性尚未公开。培养条件 target cancer metabolismWebPhosphorylated IRF3 forms a dimer that translocates to the nucleus and induces type I IFNs and other cytokines. After activation by STING, TBK1 and its homolog IκB kinase epsilon (IKKε) can both lead to activation of the IKK complex, which then activates the transcription factor nuclear factor κB (NF-κB) (11, 12). target canes and walking sticks