WebStatins should be used with caution in patients at increased risk of muscle toxicity, such as the elderly, those with a personal or family history of muscular disorders, history of … WebTable 5. Statin Dose Intensity and Equivalency Chart* Statin Intensity %LDL-C Reduction HMG-CoA Reductase Inhibitor Rosuvastatin Atorvastatin Pitavastatin Simvastatin …
Frontiers High-Intensity Statin vs. Low-Density Lipoprotein ...
WebMar 17, 2024 · Risk discussion: use moderate-intensity statins and increase to high-intensity with risk enhancers. Option of CACs to risk stratify if there is uncertainty about risk. If CAC = 0, can avoid statins and repeat CAC in the future (5-10 years), the exceptions being high-risk conditions such as diabetes, family history of premature CHD, and smoking. WebMay 8, 2012 · Two large prospective randomized studies, the Heart Protection Study (simvastatin at 40 mg/day) and Stroke Prevention by Aggressive Cholesterol Reduction (SPARCL; atorvastatin at 80 mg) demonstrated that high-dose statins can be used safely over prolonged periods of time. 7, 8 Statins at maximum doses are well tolerated with … cessnock medical
Cholesterol Management: ACC/AHA Updates Guideline AAFP
WebTable 2. Categories of Intensities of Statins. Drug Low-Intensity 20-25% ↓ LDL-C Moderate-Intensity ... 2024 Focused Update of the 2016 ACC Expert Consensus Decision Pathway on the Role of Non-Statin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk: A Report of the American College of ... WebStatins were classified by strength, with rosuvastatin <10 mg, atorvastatin <20 mg, and simvastatin <80 mg classed as low-/medium-intensity according to NICE guidelines; and a more pragmatic classification based on a statin intensity threshold of 37% reduction in LDL, with rosuvastatin 5 mg, atorvastatin 10 mg, and simvastatin 40 mg additionally … WebFeb 26, 2024 · Based on high-quality evidence from RCTs, moderate-intensity statin therapy should be initiated without calculating a 10-year ASCVD risk for all patients 40 to 75 years … buzzfeed introvert extrovert quiz